It is so interesting to observe the change in my personality and cognition since taking Ozempic. I started in the first week of January, it may have even been the 5th of January, and when I read back on my journal, I can see some changes in my emotional reactions straight away.

Ozempic affects our dopamine reward circuits. That is why we don’t feel like eating (or often doing anything else). I noticed that my libido was one of the first things to crash. And then I noticed that I didn’t want to go out and DO STUFF. At the time, I thought that it was a symptom of my relationship troubles, and while that likely was a factor, I am wondering now, how the whole ecosystem of my emotional world may have changed significantly with the addition of GLP-1 to my cocktail of medications.

Mostly, I notice the changes in my psychology when I am looking back on it. I simply had less energy and passion generally.

The first time I noticed something particularly related to my cognition was a nice day when I finally went out and got into the world again. It left me feeling so energised, and so happy. Then back to the doldrums.

When the person said that ‘weight might not be the only thing you lose’, they were referring to their personality. I have lost some of mine too. I am harder to talk to now, I know that. Hopefully it will be temporary, but I am not at all sure that it will be the case.

It is the strangest thing, because at times I feel like my mind is so much more active, even at rest, but other times, I can’t concentrate on a group conversation, and I simply am not ‘engaged’ in a way that I always was before.